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2014 Modeling TB-HIV Syndemic and Treatment
Cristiana J. Silva, Delfim F. M. Torres
J. Appl. Math. 2014(SI05): 1-14 (2014). DOI: 10.1155/2014/248407


Tuberculosis (TB) and human immunodeficiency virus (HIV) can be considered a deadly human syndemic. In this paper, we formulate a model for TB and HIV transmission dynamics. The model considers both TB and acquired immune deficiency syndrome (AIDS) treatment for individuals with only one of the two infectious diseases or both. The basic reproduction number and equilibrium points are determined and stability is analyzed. Through simulations, we show that TB treatment for individuals with only TB infection reduces the number of individuals that become coinfected with TB and HIV/AIDS and reduces the diseases (TB and AIDS) induced deaths. Analogously, the treatment of individuals with only AIDS also reduces the number of coinfected individuals. Further, TB treatment for coinfected individuals in the active and latent stage of TB disease implies a decrease of the number of individuals that passes from HIV-positive to AIDS.


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Cristiana J. Silva. Delfim F. M. Torres. "Modeling TB-HIV Syndemic and Treatment." J. Appl. Math. 2014 (SI05) 1 - 14, 2014.


Published: 2014
First available in Project Euclid: 1 October 2014

zbMATH: 07131444
Digital Object Identifier: 10.1155/2014/248407

Rights: Copyright © 2014 Hindawi

Vol.2014 • No. SI05 • 2014
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