September 2012 A branching process for virus survival
J. Theodore Cox, Rinaldo B. Schinazi
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J. Appl. Probab. 49(3): 888-894 (September 2012). DOI: 10.1239/jap/1346955342

Abstract

Quasispecies theory predicts that there is a critical mutation probability above which a viral population will go extinct. Above this threshold the virus loses the ability to replicate the best-adapted genotype, leading to a population composed of low replicating mutants that is eventually doomed. We propose a new branching model that shows that this is not necessarily so. That is, a population composed of ever changing mutants may survive.

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J. Theodore Cox. Rinaldo B. Schinazi. "A branching process for virus survival." J. Appl. Probab. 49 (3) 888 - 894, September 2012. https://doi.org/10.1239/jap/1346955342

Information

Published: September 2012
First available in Project Euclid: 6 September 2012

zbMATH: 1277.60186
MathSciNet: MR3012108
Digital Object Identifier: 10.1239/jap/1346955342

Subjects:
Primary: 60K37
Secondary: 92D25

Keywords: branching process , Evolution , Quasispecies , random environment

Rights: Copyright © 2012 Applied Probability Trust

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Vol.49 • No. 3 • September 2012
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