Electronic Journal of Statistics

Bootstrapping Aalen-Johansen processes for competing risks: Handicaps, solutions, and limitations

Dennis Dobler and Markus Pauly

Full-text: Open access

Abstract

Statistical inference in competing risks models is often based on the famous Aalen-Johansen estimator. Since the corresponding limit process lacks independent increments, it is typically applied together with Lin’s (1997) resampling technique involving standard normal multipliers. Recently, it has been seen that this approach can be interpreted as a wild bootstrap technique and that other multipliers, e.g. centered Poissons, may lead to better finite sample performances, see Beyersmann et al. (2013). Since the latter is closely related to Efron’s classical bootstrap, the question arises whether this or more general weighted bootstrap versions of Aalen-Johansen processes lead to valid results. Here we analyze their asymptotic behaviour and it turns out that such weighted bootstrap versions in general possess the wrong covariance structure in the limit. However, we demonstrate that the weighted bootstrap can nevertheless be applied for specific null hypotheses of interest and also discuss its limitations for statistical inference. To this end, we introduce different consistent weighted bootstrap tests for the null hypothesis of stochastically ordered cumulative incidence functions and compare their finite sample performance in a simulation study.

Article information

Source
Electron. J. Statist., Volume 8, Number 2 (2014), 2779-2803.

Dates
First available in Project Euclid: 8 January 2015

Permanent link to this document
https://projecteuclid.org/euclid.ejs/1420726191

Digital Object Identifier
doi:10.1214/14-EJS972

Mathematical Reviews number (MathSciNet)
MR3299122

Zentralblatt MATH identifier
1309.62079

Subjects
Primary: 62G09: Resampling methods 62N03: Testing 62G10: Hypothesis testing
Secondary: 62M02: Markov processes: hypothesis testing

Keywords
Aalen-Johansen estimator bootstrap competing risk counting processes cumulative incidence function left-truncation right-censoring weighted bootstrap

Citation

Dobler, Dennis; Pauly, Markus. Bootstrapping Aalen-Johansen processes for competing risks: Handicaps, solutions, and limitations. Electron. J. Statist. 8 (2014), no. 2, 2779--2803. doi:10.1214/14-EJS972. https://projecteuclid.org/euclid.ejs/1420726191


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